Sixty years of CA: a cancer journal for clinicians.

Prostate cancer screening rates remain stable despite recommendations against testing men with limited life expectancy.

The balance of benefits and harms of screening for prostate cancer are controversial. In 2008, the US Preventive Services Task Force issued a guideline that recommended against PSA-based screening for men aged 75 years and older because the likelihood of benefit from screening men with approximately 10 years of remaining life expectancy (RLE) was low. This was updated in 2012 to recommend again...

Sensitivity and Specificity of CA 15-3 in Detection of Breast Cancer Recurrence

Background: The value of CA15-3(cancer antigen 15-3) marker in early detection of breast cancer recurrence has been studied in several prospective trials. But the results of these studies are different. This may be due to variable cutoff points used for analysis, different intervals between CA15-3 measurements and the differences between patients population. This study was done to examine the p...

Cancer control opportunities in low- and middle-income countries.

Fecal occult blood testing remains a valuable screening tool.

Both colonoscopy and FOBT are options for CRC screening. For those at an average risk of developing CRC, screening should start at age 50 years. The 2 screening options most often selected are colonoscopy every 10 years and annual FOBT. While FOBT is noninvasive, if a positive result is found, then a colonoscopy is recommended. Over the course of multiple years of screening, false-positive FOBT...

American Cancer Society guidelines for the early detection of breast cancer: update 1997.

The American Cancer Society (ACS) convened a workshop in March 1997 to consider new scientific findings related to breast cancer screening and to determine whether these findings warrant a change in the existing ACS guidelines. The meeting was timed so that participants could benefit from new data related to screening women aged 40 to 49 years. A recommendation based on the new data and subsequ...